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Titration curves characterizing the interaction of Fpg (A), OGG1 (B), Nei (C), NEIL1 (D), and NTH1 (E) with a native duplex without damage (C/G), a duplex containing an F-site (F/G), an undamaged G-quadruplex (Q4), and G-quadruplexes with Tg or oxoG (Q4-Tg or Q4-oxoG). Concentration of DNA was 0.5 μM. Titration was performed in the following buffer: 50 mM Tris–HCl pH 7.5, 50 mM KCl, 1 mM EDTA, 1 mM DTT, and 7% of glycerol.
