Table 2.
Multivariate logistic regression analysis comparing wards patients against critically ill patients (Enter method)
| OR [CI95%] | p | OR [CI95%] | p | OR [CI95%] | p | |
|---|---|---|---|---|---|---|
| Sex (male) | 2.055 [0.656–6.432 | 0.216 | 1.647 [0.508–5.337] | 0.406 | 1.608 [0.500–5.166] | 0.425 |
| Systolic pressure (mmHg) | 0.985 [0.960–1.011 | 0.253 | 0.984 [0.958–1.011] | 0.247 | 0.984 [0.957–1.012] | 0.261 |
| O2 Saturation (%) | 1.069 [0.986–1.160] | 0.107 | 1.076 [0.992–1.167] | 0.079 | 1.082 [0.993–1.180] | 0.071 |
| Bilateral pulmonary infiltrate | 2.343 [0.469–11.707] | 0.300 | 3.088 [0.566–16.852] | 0.193 | 3.064 [0.539–17.430] | 0.207 |
| Glucose (mg/dl) | 1.008 [1.001–1.015] | 0.028 | 1.007 [1.000–1.015] | 0.061 | 1.007 [0.999–1.014] | 0.070 |
| INR | 1.123 [0.433–2.915] | 0.812 | 1.245 [0.469–3.305] | 0.661 | 1.377 [0.519–3.657] | 0.521 |
| D-dimer (pg/mL) | 1.000 [1.000–1.000] | 0.294 | 1.000 [1.000–1.000] | 0.190 | 1.000 [1.000–1.000] | 0.420 |
| LDH (UI/L) | 1.009 [1.004–1.014] | 0.000 | 1.008 [1.003–1.013] | 0.002 | 1.009 [1.004–1.014] | 0.001 |
| GPT (UI/L) | 1.005 [0.992–1.019] | 0.443 | 1.005 [0.991–1.019] | 0.516 | 1.006 [0.992–1.021] | 0.402 |
| Ferritin (pg/mL) | 1.000 [1.000–1.000] | 0.705 | 1.000 [1.000–1.000] | 0.856 | 1.000 [1.000–1.000] | 0.835 |
| CRP (mg/dl) | 0.998 [0.992–1.003] | 0.420 | 0.999 [0.993–1.005] | 0.749 | 0.998 [0.993–1.004] | 0.547 |
| Haematocrit (%) | 0.770 [0.676–0.877] | 0.000 | 0.762 [0.665–0.872] | 0.000 | 0.737 [0.633–0.858] | 0.000 |
| SARS-CoV-2 IgG (Yes) | 1.967 [0.627 -6.170] | 0.246 | 1.835 [0.562–5.987] | 0.315 | 1.918 [0.577–6.377] | 0.288 |
| Lymphocytes (cells/mm3) | 0.998 [0.996–1.000] | 0.011 | 0.998 [0.996–1.000] | 0.012 | 0.998 [0.996–0.999] | 0.010 |
| Monocytes (cells/mm3) | 0.998 [0.995–1.001] | 0.180 | 0.998 [0.995–1.001] | 0.212 | 0.999 [0.996–1.002] | 0.463 |
| Neutrophils (cells/mm3) | 1.000 [1.000–1.000] | 0.262 | 1.000 [1.000–1.000] | 0.326 | 1.000 [1.000–1.000] | 0.239 |
| Viral RNAemia (Yes) | 3.916 [1.183–12.968] | 0.025 | – | – | – | – |
|
Viral RNA load (N1) in plasma, log (copies/mL) |
– | – | 1.962 [1.244–3.096] | 0.004 | – | – |
|
Viral RNA load (N2) in plasma, log (copies/mL) |
– | – | – | – | 2.229 [1.382–3.595] | 0.001 |
The association between viral RNAemia or viral RNA load targeting the N1 region, or viral RNA load targeting the N2 region with critical illness was evaluated adjusting by major confounding factors