Table 3.
Demographic characteristics of LonGenity cohort at baseline by MCR status
| No MCR* (n=501) |
Incident MCR (n=70) |
|
|---|---|---|
| Age, mean ± SD, y | 75.03±6.34 | 75.05±6.52 |
| Women, n (%) | 291(58.1) | 34(48.6) |
| Education, mean y | 17.59±2.75 | 17.79±2.79 |
| Frailty index, Mean± SD | 0.15±0.07 | 0.17±0.08 |
| Social vulnerability index, Mean± SD | 0.10±0.09 | 0.12±0.11 |
| Medical illnesses | ||
| Global health score, mean ± SD** | 0.97±0.91 | 1.30±1.07 |
| Hypertension, n (%) | 197(39.3) | 40(57.1)* |
| Myocardial infarction, n (%) | 25(5.0) | 8(11.4) |
| Congestive heart failure, n (%) | 3(0.6) | 1(1.4) |
| Stroke, n (%) | 9(1.8) | 6(8.6)* |
| Cancer, n (%) | 173(34.5) | 24(34.3) |
| Diabetes, n (%) | 36(7.2) | 9(12.9) |
| Chronic lung disease, n (%) | 12(2.4) | 2(2.9) |
| Arthritis, n (%) | 200(40.0) | 25(35.7) |
| Parkinson, n (%) | 5(1.0) | 0(0) |
| Depression, n (%) | 96(19.2) | 16(22.9) |
| Cognitive tests | ||
| FCSRT free recall, mean (SD) | 33.80±5.22 | 33.27±4.80 |
| DSST, mean (SD) | 61.32±14.38 | 56.64±13.00 |
*
No MCR: participants who were free from MCR at baseline as well as throughout the study follow-up.
*
Significant difference in diseases prevalence at baseline when incident MCR participants were compared with non-MCR group.
**
Presence or absence of physician diagnosed depression, diabetes, heart failure, hypertension, myocardial infarction, strokes, Parkinson's disease, chronic obstructive lung disease, and arthritis was used to calculate a global health score (range 0–9) as previously described.[4]