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. 2020 Dec 11;19:1533033820977546. doi: 10.1177/1533033820977546

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — miRNA-195 regulates the proliferation and apoptosis of SCLC cells through Rap2C. Empty vector and Rap2C were transfected into miRNA-195 overexpressed SCLC cells. A: CCK-8 assay was used to detect cell viability. B: Apoptotic rates were analyzed by using flow cytometry. C: Western blot analysis of Bax, Bcl-2 expression. D: MiRNA-195-overexpressed SCLC cells transfected with Rap2C or control vector were subcutaneously injected in nude mice. Tumor volume was evaluated.