Figure 11.

Dose–response curves of carbon–diazocine-functionalized axitinib derivative 7 in an in vitro VEGFR-2 kinase assay with and without irradiation. Data points are means of double determinations with their standard deviation as error bars. Final DMSO concentration 10%. Z-7 in the dark (red, residual activity: ≥ 37%) as well as after irradiation at 405 nm (blue, IC₅₀ = 493 nM, R² = 0.89).