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Synthesis of metallated carbon–diazocine 44 and subsequent Stille coupling. Reaction conditions: (i) 1. KOtBu, THF, 0 °C, 2 min, 2. Br2, 0 °C, 5 min; (ii) SnCl2, ethyl acetate, reflux, 4 h, 26%; (iii) mCPBA, acetic acid, RT, 6 h, 51%; (iv) Sn2Me6, Pd(PPh3)4, dry toluene, 100 °C, microwave, 4 h, 51%; (v) Pd(PPh3)4, DMF, 120 °C, 24 h, 31%.
