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Quadruplex structures. (A) Chemical structure of a G4. (B) Chemical structure of an i-Motif. (C) NMR solution structure of a tetrameric parallel G4 (Protein Data Bank: 139D) from different rotation angles. (D) NMR solution structure of an alternating antiparallel tetrameric G4 (Protein Data Bank: 6IMS) from different rotation angles. (E) NMR solution structure of a tetrameric i-Motif (Protein Data Bank: 1YBL) from different rotation angles.
