Table 4. Percentage Inhibitions Measured for Key Compounds in Table 3 against Different Kinases in-House.
FLT3 |
CDK2 |
AURA |
GSK3B |
MUSK |
||||||
---|---|---|---|---|---|---|---|---|---|---|
ID | 0.1 μMa | 1.0 μMa | 0.1 μMa | 1.0 μMa | 0.1 μMa | 1.0 μMa | 0.1 μMa | 1.0 μMa | 0.1 μMa | 1.0 μMa |
19 | 87 | 94 | 44 | 81 | 3 | 19 | 46 | 86 | 14 | 28 |
22 | 82 | 92 | 20 | 69 | 0 | 13 | 47 | 84 | 13 | 18 |
24 | 42 | 70 | 0 | 10 | 0 | 0 | 0 | 6 | 0 | 4 |
25 | 34 | 64 | 9 | 15 | 6 | 5 | 12 | 16 | 7 | 10 |
Indicates compound concentration.