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. 2020 Oct 14;11(12):2374–2381. doi: 10.1021/acsmedchemlett.0c00255

Table 7. Mean Plasma and Tumor Concentrations of Compound 24 after Repeated Oral Administration in OCI-Ly3 Tumor Bearing Mice.

Treatment groups Mean plasma conc (ng/mL) Mean tumor conc (ng/g)
25 mg/kg 5077.8 ± 587.5 2667.2 ± 399.7
50 mg/kg 11565.9 ± 1074.7 8291.2 ± 1013.3
100 mg/kg 23268.2 ± 2280.2 17943.3 ± 2122.6
200 mg/kg 39123.0 ± 3101.2 36973.7 ± 2622.5