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. Author manuscript; available in PMC: 2020 Dec 14.
Published in final edited form as: Am J Hematol. 2020 Apr 21;95(7):766–774. doi: 10.1002/ajh.25799

TABLE 3.

Relationship of baseline medical history with death. P values were calculated from log rank test for equality of survival

N Alive N Died P (log rank test)
Chronic transfusion program, no. {%) 479 64 (13.4%) 10 6 (60.0%) <.001a
History of stroke, no. (%) 482 47 (9.8%) 10 5 (50.0%) .001a
Age ≥ 13 years, no. (%) 487 227 (46.6%) 10 9 (90.0%) .008a
History of asthma, no (%) 483 113 (23.4%) 10 6 (60.0%) .009a
3+ Severe pain episodes past year, no. (%) 487 91 (18.6%) 10 5 (50.0%) .013a
oc-thalassemia gene deletion, no. (%) 459 147 (32.0%) 9 5 (55.6%) .09
History of ACS or pneumonia, no (%) 482 232 (48.1%) 10 7 (70.0%) .17
Hemoglobin SS genotype, no (%) 487 364 (74.7%) 10 8 (80.0%) .70
Male gender, no (%) 487 248 (50.9%) 10 6 (60.0%) .64
Hydroxyurea treatment, no (%) 483 177 (36.6%) 10 4 (40.0%) .88
a

Significant after adjusting for multiple hypothesis testing using False Discovery Rate < 0.05.