Table 2.
Baseline blood pressure category | Number of patients | HBP measurement days (times) | |||||
First | Second | Third | Forth | Fifth | P value | ||
Pretreatment, mm Hg | |||||||
All | 2423 | 152.5 (14.7) | 152.5 (14.8) | 152.2 (14.9) | 152.4 (14.6) | 152.6 (14.9) | 0.48 |
<145 | 763 | 140.3 (9.1) | 139.6 (8.4) | 139.1 (8.8) | 139.7 (8.2) | 140.4 (9.6) | 0.032 |
145–154 | 699 | 149.6 (9.9) | 150.0 (9.4) | 149.5 (9.7) | 149.5 (9.2) | 149.5 (9.5) | 0.85 |
155–164 | 544 | 159.3 (10.3) | 158.7 (10.3) | 159.5 (9.6) | 159.8 (9.7) | 159.8 (10.5) | 0.41 |
≥165 | 417 | 170.9 (11.3) | 172.0 (10.3) | 171.1 (10.4) | 171.0 (11.2) | 171.4 (11.5) | 0.66 |
Monotherapy, mm Hg | |||||||
All | 2423 | 145.5 (17.0) | 145.2 (16.9) | 145.4 (16.5) | 145.4 (16.5) | 144.7 (16.6) | 0.58 |
<145 | 763 | 135.3 (13.2) | 135.1 (13.1) | 135.5 (13.4) | 135.8 (13.2) | 135.1 (13.1) | 0.56 |
145–154 | 699 | 143.8 (13.8) | 143.1 (13.3) | 143.3 (13.0) | 142.9 (13.3) | 141.9 (12.9) | 0.035 |
155–164 | 544 | 150.2 (15.3) | 150.5 (15.4) | 150.5 (14.6) | 151.2 (14.4) | 150.5 (14.7) | 0.67 |
≥165 | 417 | 161.1 (16.5) | 160.0 (17.0) | 160.3 (15.4) | 160.1 (16.1) | 160.5 (15.9) | 0.65 |
Values are expressed as the arithmetic mean (SD). The numbers of patients with missing blood pressure data on the fourth and fifth days were 38 and 84 at pretreatment and 87 and 286 during monotherapy, respectively, while p values were calculated by a repeated measure mixed linear model to take missing values into account and represent the differences among the five systolic HBP values according to the measurement day at baseline during pretreatment.
Differences between the adjacent days were not significant during pretreatment (p≥0.12) or monotherapy (p≥0.14).
HBP, home blood pressure.