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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Mol Carcinog. 2020 Aug 20;59(10):1227–1240. doi: 10.1002/mc.23251

Figure 1. Combinatorial effects of BMJ and GEM against human PanC cells.

Figure 1.

Effect on total cell number and percent dead cells of (A) BxPC3, (B) AsPC1 and (C) PANC1 cells with varying concentrations of BMJ, GEM and a combination of BMJ+GEM for 72 hours. (D) Represents the combination indices for BMJ+GEM for BxPC3, AsPC1 and PANC1 cells (as determined by data from viability assays using non-constant combination ratios with Chou-Talalay method employing CompuSyn software program) after 72 hrs of drug exposure. Fa represents the fraction of cells that is growth-inhibited in response to drug treatments and is calculated as 1-fraction of surviving cells. ***p≤0.001, **p≤0.01 and *p≤0.05.