Table 1.
Associations between circRNA_0000392 levels and clinical parameters in colorectal cancer patients (n = 40)
| Characteristic | No. of Patients (%) | CircRNA-0000392 expression | P-value (2-ΔCt Mean ± SD) |
|---|---|---|---|
| Age (y) | 40 (100) | ||
| ≥60 | 31 (77.5) | 5.458 ± 5.084 | 0.3699 |
| < 60 | 9 (22.5) | 7.247 ± 5.645 | |
| Sex | 40 (100) | ||
| Men | 27 (67.5) | 5.497 ± 5.337 | 0.5310 |
| Women | 13 (32.5) | 6.615 ± 5.010 | |
| Tumor size (cm) | 40 (100) | ||
| ≥5 | 18 (45) | 5.839 ± 4.716 | 0.9810 |
| < 5 | 22 (55) | 5.879 ± 5.668 | |
| Tumor location | 40 (100) | ||
| Left hemicolon | 34 (85) | 5.365 ± 4.880 | 0.1536 |
| Right hemicolon | 6 (15) | 8.668 ± 6.497 | |
| pTNM stage | 40 (100) | ||
| I-II | 20 (50) | 4.071 ± 3.144 | 0.0123* |
| III-IV | 20 (50) | 7.679 ± 6.294 | |
| Lymph node metastasis | 40 (100) | ||
| pN negative | 21 (52.5) | 3.756 ± 3.416 | 0.0055** |
| pN positive | 19 (47.5) | 8.218 ± 5.957 | |
| Distant metastasis | 40 (100) | ||
| pM negative | 34 (85) | 4.981 ± 3.995 | 0.0084** |
| pM positive | 6 (15) | 10.940 ± 8.520 |
* P < 0.05; ** P < 0.01