Table 1. Intestinal Structures across Diverse Organisms.

This table reviews the cell types and physical barriers present in the intestine of nematodes, Drosophila, and mammals. It also lists the homeostatic mechanisms present in the intestine and the 3D structures the intestine is organized into across species.

	Epithelial Cell types	Homeostatic Maintenance	Physical Barriers	3D structures
Nematodes	Enterocytes	None	Glycocalyx	None
Drosophila melanogaster	Enterocytes Intestinal Stem Cells Enteroendocrine Cells	Local Stem Cell Proliferation (turnover ~1 week)	Peritrophic matrix Mucus	Looping
Mammals	Enterocytes Intestinal Stem Cells Enteroendocrine Cells Paneth Cells Tuft Cells Goblet Cells M Cells	Local Stem Cell Proliferation (turnover ~ 3–5 days)	Mucus	Looping Crypts Villi