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. 2020 Dec 14;15(12):e0243741. doi: 10.1371/journal.pone.0243741

Table 1. Demographic and clinical characteristics.

Characteristicsa All cases
Pairs of episodes 693
Number of patients 483
Years of recruited cases
 • 2014 65 (9.4)
 • 2015 103 (14.9)
 • 2016 149 (21.5)
 • 2017 127 (18.3)
 • 2018 99 (14.3)
 • 2019 150 (21.6)
Age (years)b 59 [28–71]
Gender
 • Female 401 (57.4)
 • Male 292 (42.1)
Comorbidty
 • No 150 (21.6)
 • Yes 543 (78.4)
Interval between paired isolates (months)b 3 [2–5]
Reasons of admission
 • Medical reasons 602 (86.9)
 • Surgical reasons 91 (13.1)
Presence of urological/surgical condition
 • No 390 (56.3)
 • Yes 303 (43.7)
Type of previous microorganism
 • E. coli 570 (82.3)
 • K. pneumoniae 123 (17.7)
Results of current urine cultures
 • ESBL-positive 406 (58.6)
 • No growth 83 (12.0)
 • Mixed growth 110 (15.9)
 • Non-ESBL producers 86 (12.4)
 • Fungi 8 (1.1)
Outpatients cultures
 • No 555 (80.1)
 • Yes 138 (19.9)
Medication allergy
 • No 664 (95.8)
 • Yes 29 (4.2)
Concordance of empirical therapy
 • Non-concordant 270 (39)
 • Concordant 423 (61)

a All data expressed as n (%) of participants unless otherwise indicated.

b Data described as median [Interquartile range].