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. 2020 Dec 14;15(12):e0243900. doi: 10.1371/journal.pone.0243900

Table 1. Clinicopathological characteristics of patients included.

Characteristic n
Sex
    Male/Female (%) 79/57 (58/42)
Median age (range) 62 years (25–90)
Ki-67
    ≤55% / >55% (range) 50/86 (20–100)
Chromogranin A
    Positive 108
    Negative 28
Synaptophysin
    Positive 129
    Negative 7
Primary Tumor
    Oesophageal 5
    Gastric 11
    Pancreatic 23
    Colonic 35
    Rectal 10
    CUP 41
    Other GI 11
Type of sample specimen
    Surgical 83
    Surgical biopsy 16
    Biopsy 37
Histological differentiation
    Well differentiated 10
    Poorly differentiated 73
    Data not available 53
Response according to RECIST criteria
    Complete response 5
    Partial response 37
    Stable disease 36
    Progressive disease 38
    Missing data 20
Metastases at diagnosis
    Liver 87
    Lymph node 29
    Lung 11
    Bone 3
    Brain 6
Pathology
    Small cell 44
    Large cell 92
PD-L1 Immunoreactivity
    Positive 14
    Negative 122