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Ultrastructural analysis of SCC-25 and UPCI:SCC-154. (A) Sections of SCC-25 spheroids embedded in the resin and visualized with an optical microscope. (B) Sections of SCC-25 spheroids on copper grids visualized by a transmission electron microscope at low magnification mode. (C) Ultrastructural analysis of 2D and 3D culture of SCC-25 and UPCI:SCC-154. Arrows indicate pools of the virus inside UPCI:SCC-154 cells (left column) and tight junctions in SCC-25 (right column).
