Table 1. Thermodynamic Parameters of the Interactions between Dopamine and Liposomes Determined by ITC Experimentsa.
system | ΔHDA (kJ mol–1) | KA (M–1) | ΔG (kJ mol–1) | TΔS (kJ mol–1) | ΔS (J K–1 mol–1) |
---|---|---|---|---|---|
POPS | –12.8 ± 0.1 | 1752 ± 95 | –18.5 ± 0.2 | 5.73 ± 0.14 | 19.2 ± 0.5 |
POPC/SM/Chol | –4.66 ± 0.04 | 305.6 ± 15.0 | –14.2 ± 0.2 | 9.59 ± 0.12 | 32.2 ± 0.4 |
Results are given for the association enthalpy of dopamine to liposomes (ΔHDA); association constant (KA); Gibbs free energy (ΔG); entropic component in the free energy; and a change in entropy (ΔS).