Table 2. Permeability Coefficient and Fraction of Bound CA II at Plateau Calculated for Each Compound from the Nonlinear Fitting of the Dose- and Time-Dependent Binding Data.
n | KP × A (dm3 s–1) | bound CA II at plateau |
---|---|---|
1 | (2.8 ± 0.7) × 10–7 | 78 ± 3% |
2 | >6 × 10–7 | 53 ± 2% |
3 | >6 × 10–7 | 86 ± 5% |
4 | (1.6 ± 0.4) × 10–8 | 100% |
5 | (1.8 ± 0.2) × 10–8 | 100% |
6 | >6 × 10–7 | 36 ± 5% |
7 | >6 × 10–7 | 100% |
8 | (5.4 ± 0.3) × 10–7 | 100% |
9 | >6 × 10–7a | 100% |
Previously measured KP × A = 1.2 × 10–6 dm3 s–1.13