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. 2020 Sep 21;15(10):2792–2800. doi: 10.1021/acschembio.0c00590

Table 2. Permeability Coefficient and Fraction of Bound CA II at Plateau Calculated for Each Compound from the Nonlinear Fitting of the Dose- and Time-Dependent Binding Data.

n KP × A (dm3 s–1) bound CA II at plateau
1 (2.8 ± 0.7) × 10–7 78 ± 3%
2 >6 × 10–7 53 ± 2%
3 >6 × 10–7 86 ± 5%
4 (1.6 ± 0.4) × 10–8 100%
5 (1.8 ± 0.2) × 10–8 100%
6 >6 × 10–7 36 ± 5%
7 >6 × 10–7 100%
8 (5.4 ± 0.3) × 10–7 100%
9 >6 × 10–7a 100%
a

Previously measured KP × A = 1.2 × 10–6 dm3 s–1.13