Fig 4. EOL-1 protein forms cytoplasmic foci if mitochondria are dysfunctional.
(A) EOL-1 protein, but not DRH-1 protein form puncta in the hsp-6(mg585) mitochondrial mutant but not in wild type. Mitochondrial dysfunction caused by hsp-6(mg585) mutation triggered the formation of EOL-1::mScarlet foci, while mScarlet::DRH-1 remained diffusely localized. (B) EOL-1 foci are not associated with the mitochondria. In the hsp-6(mg585) mutant, the EOL-1::mScarlet foci do not colocalize with mitochondria that were visualized by the mitochondrial outer membrane protein TOMM-20::GFP.