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. 2020 Dec 10;12:12723–12733. doi: 10.2147/CMAR.S267634

Figure 3.

Figure 3

Targeting regulatory relationship between miR-139-5p and ZEB1. (A) Binding locus between miR-139-5p and ZEB1. (B) DLR result. (C, D) Up-regulation of miR-139-5p down-regulated the transcription and protein level of ZEB1. Its protein profiling.

Notes: **Indicates P<0.01 in terms of comparison with the miR-NC group. aIndicates P<0.01 in terms of comparison with the miR-139-5p group.

Abbreviations: miR, microRNA; ZEB1, zinc finger E-box-binding homeobox 1; DLR, dual luciferase reporter; NC, negative control; Wt, wild type; Mut, mutant.