FIGURE 6.

Peripheral pathology. Representative sections were taken from each organ and stained with H&E. Delta-24-MSCs were not identified in any of the peripheral organs supplied. Further, histologic and gross damage was not seen in these organs. Specifically, there was including no evidence of inflammation, ischemia, vessel occlusion or hemorrhages in any of the eight animals infused with hMSC-D24. Embolic particles were identified in the eye in subject 8 (positive control). This confirms the angiographic observation of the ophthalmic artery supply from the ICA and represents a potential complication detectable by pathology.