TABLE.
Meningioma Gene Signature Discovery and Validation Cohort Characteristics
| Discovery cohort | Validation cohort | |
|---|---|---|
| Clinical characteristic by patient | ||
| Number of unique patients | 84 | 56 |
| Median patient age | 60.4y (IQR 52.6-67.6) | 64.0 (53.0-76.0) |
| Number of male patients | 33 (39%) | 23 (41%) |
| Number of patients with recurrent meningioma at presentation | 22 (26%) | 11 (20%) |
| Number of patients with prior meningioma resections | 15 (18%) | Unknown |
| Number of patients with prior meningioma radiotherapy | 18 (21%) | 5 (9%) |
| Number of gross total resections | 39 (46%) | 47 (84%) |
| WHO grade of first resection | ||
| I | 12 (14%) | 35 (63%) |
| II | 64 (76%) | 16 (29%) |
| III | 7 (8%) | 5 (9%) |
| Median clinical follow up (yr) | 6.4 (IQR 3.6-9.1) | 5.4 (2.9-7.0) |
| Number of patients who died | 35 (42%) | 10 (18%) |
| Number of patients who died of meningioma progression | 17 (20%) | Unknown |
| Clinical characteristics by meningioma | ||
| Number of meningiomas | 96 | 56 |
| Number of meningiomas recurrent at presentation | 33 (34%) | 11 (20%) |
| Number of meningiomas with prior surgery | 19 (20%) | Unknown |
| Number of meningiomas with prior radiotherapy | 29 (30%) | 5 (9%) |
| Number of gross total resections | 45 (47%) | 47 (84%) |
| WHO grade | ||
| I | 13 (14%) | 35 (63%) |
| II | 64 (67%) | 16 (29%) |
| III | 19 (20%) | 5 (9%) |
| Number recurred | 49 (58%) | 11 (20%) |