Table 4.
Results of the Pathway Analysis of Metabolic Biomarkers
| Pathway Name | Match Status | P Value | FDR | Impact |
|---|---|---|---|---|
| Aminoacyl-tRNA biosynthesis | 11/48 | 7.59E-06 | 6.37E-04 | 0.00000 |
| Phenylalanine, tyrosine and tryptophan biosynthesis | 3/4 | 4.04E-04 | 0.01698 | 1.00000 |
| Alanine, aspartate and glutamate metabolism | 6/28 | 0.00157 | 0.04406 | 0.33974 |
| Glyoxylate and dicarboxylate metabolism | 6/32 | 0.00325 | 0.05595 | 0.05556 |
| Arginine biosynthesis | 4/14 | 0.00333 | 0.05595 | 0.07614 |
| Glycerophospholipid metabolism | 6/36 | 0.00600 | 0.08396 | 0.38978 |
| Citrate cycle (TCA cycle) | 4/20 | 0.01296 | 0.15552 | 0.21656 |
| Sphingolipid metabolism | 4/21 | 0.01544 | 0.16212 | 0.21704 |
| Lysine degradation | 4/25 | 0.02825 | 0.26366 | 0.00469 |
| Nicotinate and nicotinamide metabolism | 3/15 | 0.03142 | 0.26391 | 0.19430 |
| Tyrosine metabolism | 5/42 | 0.04629 | 0.33754 | 0.24711 |
FDR, false discovery rate.