Table 4.

Accuracy of IFN-γ assays according to 4 criteria evaluated on 718 animals.

TEST	N	TP	TN	FP	%FP	FN	%FN	SE% (CI 95%)	SP% (CI95%)	Youden's J%
Criterion 1	718	424	281	3	1.1	10	2.3	97.7 (95.8–98.9)	98.9 (96.9–98.9)	96.6
Criterion 2	718	428	276	8	2.8	6	1.4	98.6 (97.0–99.5)	97.2 (94.5–97.2)	95.8
Criterion 3	718	428	276	8	2.8	6	1.4	98.6 (97.0–99.5)	97.2 (94.5–97.2)	95.8
Criterion 4	718	345	280	4	1.4	89	20.5	79.5 (75.4–83.2)	98.6 (96.4–98.6)	78.1

N, No of animals tested; TP, true positive; TN, true negative; FP, false positive; %FP, % false positive; FN, false negative; %FN, % false negative; SE CI 95%, sensitivity and confidence interval 95%; SP CI 95%, specificity and confidence interval 95%; and Y, Youden's J.