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. Author manuscript; available in PMC: 2021 Dec 21.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 Oct 26;59(52):23668–23677. doi: 10.1002/anie.202008175

Table 1.

Top 20 most abundant proteins identified by proteomic mass spectrometry in plasma nanoparticle coronas.

Plasma PNPs in plasma (GT)15-SWCNTs in plasma
1 Serum albumin Alpha-2-HS-glycoprotein Clusterin
2 Haptoglobin Ig kappa constant Histidine-rich glycoprotein
3 Ig kappa constant Haptoglobin Apolipoprotein A-I
4 Ig heavy constant gamma Complement C3 Complement C3
5 Serotransferrin Kininogen-1 Haptoglobin
6 Apolipoprotein A-I Ig heavy constant gamma 1 A disintegrin and metalloproteinase with thrombospondin motifs 12
7 Complement C4 Apolipoprotein A-II Complement C1r subcomponent
8 Telomeric repeat-binding factor 2-interacting protein tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like Vitronectin
9 Alpha-1-antitrypsin Beta-2-glycoprotein 1 Kininogen-1
10 Alpha-2-HS-glycoprotein Vitronectin Prothrombin
11 Apolipoprotein A-II Serum albumin C4b-binding protein alpha chain
12 Ig heavy constant alpha 1 Vitamin D-binding protein Complement factor H
13 Integrin alpha-7 A disintegrin and metalloproteinase with thrombospondin motifs 12 Fibrinogen alpha chain
14 Alpha-2-macroglobulin Hemopexin Protein AMBP
15 Complement C3 Apolipoprotein A-I Beta-2-glycoprotein 1
16 Complement C5 Ig lambda-like polypeptide 5 Apolipoprotein E
17 Hemopexin Histidine-rich glycoprotein Complement C1q subcomponent subunit B
18 Alpha-1-acid glycoprotein 1 Clusterin Ig heavy constant gamma 1
19 Ig heavy constant mu Alpha-1-antitrypsin Ig J chain
20 Beta-2-glycoprotein 1 Serum paraoxonase/arylesterase 1 Galectin-3-binding protein