Table 1.
Characteristics of articles involved in the meta-analysis.
| Study | Country | Extract | Animal model | Gender | Number per group | Dose(mg/kg) | Duration (weeks) | Outcome |
|---|---|---|---|---|---|---|---|---|
| Jiang et al. (31) | China | Ethanol, Aqueous | KM mice + HFD | Male | 10 | Ethanol 1,500 Aqueous 1,500 |
10 | TC, TG, HDL, LDL |
| Kurihara et al. (32) | Japan | Aqueous | KK-Ay | Male | 11 | 2,000 | 3 | BG |
| Li et al. (33) | China | Aqueous | SD rats + HFD + STZ (35 mg/kg) | Male | 6 | 200 | 12 | BG, TC, TG |
| Liu et al. (15) | China | Ethanol, Aqueous | C57BL/6 mice + HFD + STZ (40 mg/kg) | Male | 6 | Ethanol 8,000 (5 groups) Aqueous 8,000 (5 groups) |
4 | BG, TC, TG, HDL, LDL, OGTT |
| Ma et al. (11) | China | Ethanol | KM mice + HFD | Male | 8 | Ethanol 370/750/1,500 | 4 | TC, TG, HDL, LDL |
| Sheng et al. (17) | China | Aqueous | SD rats + HFD + alloxan (105 mg/kg) | Male | 8 | Aqueous 1,000 | 5 | BG, TC, TG, HDL, LDL, OGTT |
| Wang et al. (16) | China | Ethanol, Aqueous | SD rats + HFD + 5% sucrose-containing water + STZ (30 mg/kg) | Male | 6 | Ethanol 2,000/4,000/8,000 Aqueous 2,000/4,000/8,000 |
4 | BG, TC, TG, HDL, LDL |
| Wang et al. (34) | China | Aqueous | Wistar rats + HFD + STZ (35 mg/kg) | Male | Model:13 Low dose: 9 High dose: 11 |
Aqueous 47/94 | 8 | BG |
| Xiao et al. (9) | China | Aqueous | C57/BL6J mice + HFD + STZ (25 mg/kg) | Male | 8 | Aqueous 1,000/2,000/4,000 | 5 | BG, TC, TG, HDL, LDL, OGTT |
| Xu et al. (10) | China | Aqueous | SHR/cp rats | Male | 6 | Aqueous 500 | 7 | BG, TC, TG |
| Zhao et al. (8) | China | Ethanol | C57BL/6J mice + HFD + STZ (40 mg/kg) | Male and Female | 5 | Ethanol 500 | 4 | BG, OGTT |
BG, blood glucose level; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OGTT, oral glucose tolerance test; TC, total cholesterol; TG, triglycerides.