TABLE 3.
Proteins in the C category (Energy production and conversion) modulated during P. freudenreichii growth in soy ultrafiltrate compared to cow’s milk ultrafiltrate.
| Accession | Description(a) | Ratio(b) | Adjusted p-value |
| CDP48125.1 | FAD-dependent pyridine nucleotide-disulphide oxidoreductase:4Fe–4S ferredoxin, iron–sulfur binding:Aromatic-ring hydroxylase | 7.77 | 1.3E-13 |
| CDP49141.1 | Oxidoreductase | 6.18 | 6.0E-15 |
| CDP48084.1 | FAD linked oxidase domain protein | 6.03 | 2.8E-15 |
| CDP49140.1 | Iron-sulfur protein | 5.31 | 5.5E-17 |
| CDP48450.1 | Succinate dehydrogenase, subunit A | 5.06 | 8.3E-07 |
| CDP48130.1 | Glycerol-3-phosphate dehydrogenase | 3.85 | 3.8E-14 |
| CDP49203.1 | Lactaldehyde dehydrogenase | 3.77 | 2.7E-11 |
| CDP48743.1 | Anaerobic glycerol-3-phosphate dehydrogenase subunit B | 3.49 | 9.7E-14 |
| CDP48004.1 | NADH-quinone oxidoreductase chain D (NADH dehydrogenase I, chain D) | 3.24 | 1.2E-06 |
| CDP48124.1 | Pyruvate synthase/Pyruvate-flavodoxin oxidoreductase | 3.23 | 6.6E-08 |
| CDP49123.1 | Aldo/keto reductase | 3.12 | 2.1E-07 |
| CDP48449.1 | Succinate dehydrogenase, subunit B | 2.85 | 1.6E-08 |
| CDP47670.1 | NAD-dependent malic enzyme (NAD-ME) (Malate dehydrogenase) | 2.83 | 7.8E-10 |
| CDP48479.1 | Aldo/keto reductase | 2.71 | 1.6E-10 |
| CDP48801.1 | ATP synthase gamma chain (ATP synthase F1 sector gamma subunit) | 2.66 | 5.5E-05 |
| CDP48744.1 | Anaerobic glycerol-3-phosphate dehydrogenase subunit A | 2.52 | 5.7E-10 |
| CDP48000.1 | NADH-quinone oxidoreductase subunit H (NADH dehydrogenase I subunit H) | 2.46 | 1.7E-09 |
| CDP48900.1 | Citrate synthase | 2.37 | 4.3E-10 |
| CDP48006.1 | NADH-quinone oxidoreductase chain B | 2.36 | 6.3E-11 |
| CDP47836.1 | Putative isocitrate/isopropylmalate dehydrogenase | 2.31 | 1.5E-11 |
| CDP47593.1 | Succinate dehydrogenase flavoprotein subunit | 2.11 | 5.2E-12 |
| CDP48002.1 | NADH-quinone oxidoreductase chain F (NADH dehydrogenase I, chain F) (NDH-1, chain F) | 1.99 | 7.1E-12 |
| CDP49671.1 | Putative aldo/keto reductase (oxidoreductase) | 1.89 | 7.9E-09 |
| CDP49268.1 | Glycerol kinase (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK) | 1.84 | 2.1E-06 |
| CDP48742.1 | Anaerobic glycerol-3-phosphate dehydrogenase subunit C | 1.83 | 1.1E-03 |
| CDP48001.1 | NADH-quinone oxidoreductase chain G (NADH dehydrogenase I, chain G) | 1.77 | 2.6E-09 |
| CDP49441.1 | Glyoxylate reductase | 1.77 | 1.9E-09 |
| CDP48005.1 | NADH-quinone oxidoreductase chain C (NADH dehydrogenase I, chain C) | 1.76 | 2.8E-09 |
| CDP48428.1 | Pyruvate dehydrogenase E1 component (2-oxo-acid dehydrogenase E1 subunit, homodimeric type) | 1.73 | 7.9E-12 |
| CDP47592.1 | Succinate dehydrogenase | 1.72 | 3.2E-07 |
| CDP48009.1 | Electron transfer oxidoreductase | 1.72 | 2.1E-02 |
| CDP47817.1 | Zinc-binding dehydrogenase | 1.70 | 1.0E-03 |
| CDP47853.1 | NADPH:quinone reductase related Zn-dependent oxidoreductase | 1.65 | 4.9E-04 |
| CDP48708.1 | Aconitase, Aconitate hydratase | 1.60 | 8.3E-11 |
| CDP49161.1 | Methylmalonyl-CoA carboxytransferase 5S subunit (transcarboxylase 5S) 505 bp | 1.59 | 1.5E-08 |
| CDP49666.1 | Coenzyme A transferase (Putative succinyl-CoA or butyryl-CoA:coenzyme A transferase) | 1.58 | 8.1E-07 |
| CDP49604.1 | 2,5-diketo-D-gluconate reductase A | 1.56 | 5.1E-08 |
| CDP49580.1 | Electron transfer flavoprotein (FixA protein) | 1.53 | 1.5E-06 |
| CDP48091.1 | 2-oxoisovalerate dehydrogenase subunit alpha (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) | 0.64 | 6.2E-03 |
| CDP48544.1 | Phosphate acetyltransferase | 0.54 | 1.3E-09 |
| CDP49307.1 | Nitrogen-fixing NifU-like | 0.52 | 7.0E-06 |
| CDP48804.1 | ATP synthase B chain (F0F1 ATP synthase subunit B) | 0.45 | 4.8E-03 |
| CDP48090.1 | 2-oxoisovalerate dehydrogenase subunit beta (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta) Pyruvate dehydrogenase E1 component subunit beta | 0.40 | 1.6E-10 |
| CDP47988.1 | Pyruvate flavodoxin/ferredoxin oxidoreductase | 0.39 | 4.8E-06 |
(a)Determined using a database composed of the proteome of P. freudenreichii CIRM-BIA129 (downloaded from NCBI.nlm.nih.gov on 23 August 2018). (b)Ratio between the protein level in soy ultrafiltrate and in cow’s milk ultrafiltrate. This ratio indicates induction (ratio > 1.5) or repression (ratio < 0.66) during growth in soy ultrafiltrate.