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. 2020 Dec 1;11:549027. doi: 10.3389/fmicb.2020.549027

TABLE 5.

Proteins in the O category (Protein turnover and chaperone) modulated during P. freudenreichii growth in soy ultrafiltrate compared to cow’s milk ultrafiltrate.

Accession Description(a) Ratio(b) Adjusted p-value
CDP48588.1 SppA. Periplasmic serine proteases 6.05 5.7E-09
CDP47990.1 Metalloprotease (Peptidase family M13) 2.86 2.5E-03
CDP47983.1 Thioredoxin peroxidase/Alkyl hydroperoxide reductase protein C22/General stress protein 22 2.29 1.2E-13
CDP49595.1 FK506-binding protein (peptidyl-prolyl cis-trans isomerase) 2.07 1.5E-07
CDP49391.1 Probable peptidyl-prolyl cis-trans isomerase A 1.81 3.5E-10
CDP48377.1 Zn dependant peptidase 1.62 3.0E-04
CDP49065.1 Surface layer protein A (S-layer protein A) 1.56 3.1E-07
CDP47874.1 60 kDa chaperonin 1 (Protein Cpn60 1) (groEL protein 1) (Heat shock protein 60 1) 0.66 2.2E-07
CDP49125.1 60 kDa chaperonin 2 (Protein Cpn60 2) (groEL protein 2) (Heat shock protein 60 2) 0.65 1.6E-07
CDP48880.1 Thioredoxin reductase 0.64 1.7E-05
CDP48879.1 Thioredoxin 0.62 6.1E-04
CDP48050.1 Chaperone protein dnaJ 2 (DnaJ2 protein) (Heat shock protein 40 2) 0.61 6.4E-06
CDP48051.1 Protein GrpE 2 (HSP-70 cofactor 2) (Co-chaperone protein GrpE2) 0.58 6.8E-04
CDP48878.1 OsmC protein 0.53 1.0E-07
CDP49021.1 Protein GrpE 1 (HSP-70 cofactor 1) (Co-chaperone protein GrpE1) 0.49 7.6E-05
CDP49400.1 HesB protein 0.38 1.9E-12
CDP47885.1 Putative O-sialoglycoprotein endopeptidase 0.37 4.8E-08
CDP49311.1 FeS assembly protein SufD 0.36 3.6E-13
CDP49309.1 ABC-type transport system involved in Fe–S cluster assembly. ATPase component. SufC 0.33 4.2E-14
CDP49312.1 FeS assembly protein SufB 0.29 2.2E-13
CDP48273.1 Surface layer protein B 0.17 7.1E-12
CDP48858.1 Surface layer protein E 0.16 4.1E-12

(a)Determined using a database composed of the proteome of P. freudenreichii CIRM-BIA129 (downloaded from NCBI.nlm.nih.gov on 23 August 2018). (b)Ratio between the protein level in soy ultrafiltrate and in cow’s milk ultrafiltrate. This ratio indicates induction (ratio > 1.5) or repression (ratio < 0.66) during growth in soy ultrafiltrate.