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. Author manuscript; available in PMC: 2021 Oct 17.
Published in final edited form as: Adv Drug Deliv Rev. 2020 Oct 17;160:186–198. doi: 10.1016/j.addr.2020.10.008

Table 1.

Advantages of ELP and SLP as engineered protein for drug delivery.

ELASTIN LIKE PROTEIN SILK LIKE PROTEIN

  • Inverse temperature transition behavior

  • Elasticity

  • Amphiphilic, self-assembly behavior

  • Stabilization by physical crosslinks

  • Higher Mechanical Strength (robustness)
COMMON ADVANTAGES

  • Biodegradable with controlled rates of degradation by enzymes

  • Biocompatible

  • Tunable chemistry and material properties

  • Tight control of sequence and size; homogeneity in polymers and materials

  • Tailorable drug loading and release kinetics

  • Relatively low cost production and scale up