Table 2.

The characteristics of cis-mRNA-QTMs.

CHR	CpG	Gene_id	Gene	Beta	SE	P-value	Q-value
17	cg20577663	ENSG00000170425.3	ADORA2B	17.54	3.14	3.85×10−8	2.22×10−5
17	cg20577663	ENSG00000109099.9	PMP22	96.78	18.44	2.22×10−7	6.41×10−5
10	cg18975376	ENSG00000095739.7	BAMBI	11.44	2.29	8.59×10−7	1.65×10−4
10	cg18975376	ENSG00000150051.8	MKX	−4.54	0.96	2.64×10−6	3.79×10−4
2	cg04521224	ENSG00000163171.6	CDC42EP3	−3.15	0.68	4.47×10−6	5.15×10−4
13	cg25554685	ENSG00000126218.7	F10	3.73	0.82	7.25×10−6	6.96×10−4
2	cg04521224	ENSG00000115825.5	PRKD3	3.17	0.71	1.14×10−5	9.36×10−4
17	cg20577663	ENSG00000175061.10	C17orf76-AS1	170.58	41.27	4.16×10−5	3.00×10−3
2	cg24523650	ENSG00000115825.5	PRKD3	1.52	0.38	7.33×10−5	4.69×10−3
17	cg27131197	ENSG00000141030.8	COPS3	−11.53	2.92	9.05×10−5	4.94×10−3
2	cg04480325	ENSG00000115825.5	PRKD3	1.98	0.5	9.44×10−5	4.94×10−3
10	cg18975376	ENSG00000150054.12	MPP7	−3.93	1.01	1.12×10−4	5.37×10−3
2	cg06480171	ENSG00000003509.11	C2orf56	−5.52	1.43	1.35×10−4	5.97×10−3
2	cg04480325	ENSG00000115828.11	QPCT	−5.88	1.59	2.42×10−4	9.95×10−3
13	cg24074965	ENSG00000139835.8	GRTP1	3.7	1.05	4.9×10−4	0.019
13	cg24074965	ENSG00000185896.9	LAMP1	45.14	12.98	5.45×10−4	0.019
17	cg20577663	ENSG00000170315.8	UBB	−917.99	264.05	5.5×10−4	0.0198
2	cg06480171	ENSG00000163171.6	CDC42EP3	−3.89	1.12	5.82×10−4	0.019
10	cg03325931	ENSG00000150051.8	MKX	−2.23	0.65	6.8×10−4	0.02
10	cg01062834	ENSG00000183621.10	ZNF438	6.28	1.86	7.86×10−4	0.021
10	cg19826211	ENSG00000183621.10	ZNF438	8.1	2.4	7.91×10−4	0.021
2	cg04521224	ENSG00000115828.11	QPCT	−7.64	2.27	8.09×10−4	0.021
17	cg27131197	ENSG00000170425.3	ADORA2B	5.68	1.69	8.54×10−4	0.021
13	cg23119039	ENSG00000255874.1	LINC00346	0.27	0.08	8.79×10−4	0.021
10	cg20628376	ENSG00000150051.8	MKX	−1.78	0.54	1.06×10−3	0.022
13	cg25554685	ENSG00000057593.9	F7	−3.12	0.95	1.06×10−3	0.022
17	cg13180678	ENSG00000197566.5	ZNF624	1.24	0.38	1.07×10−3	0.022
2	cg04521224	ENSG00000003509.11	C2orf56	−2.87	0.88	1.12×10−3	0.022
17	cg24443925	ENSG00000109099.9	PMP22	−130.38	39.93	1.16×10−3	0.022
17	cg20577663	ENSG00000175106.12	FAM18B2	5.36	1.64	1.18×10−3	0.022
17	cg18002814	ENSG00000170425.3	ADORA2B	15.83	4.85	1.18×10−3	0.022
10	cg03325931	ENSG00000095739.7	BAMBI	5.01	1.57	1.50×10−3	0.027
17	cg18002814	ENSG00000108474.8	PIGL	−10.7	3.37	1.57×10−3	0.027
10	cg20628376	ENSG00000095787.15	WAC	20.19	6.36	1.59×10−3	0.027
2	cg06480171	ENSG00000115825.5	PRKD3	3.74	1.18	1.65×10−3	0.027
2	cg06480171	ENSG00000115828.11	QPCT	−11.64	3.73	1.89×10−3	0.030
17	cg18002814	ENSG00000109099.9	PMP22	86.49	28.41	2.45×10−3	0.038
13	cg24074965	ENSG00000057593.9	F7	−2.46	0.82	2.90×10−3	0.044
13	cg10372485	ENSG00000088448.9	ANKRD10	27.55	9.26	3.06×10−3	0.045
2	cg24523650	ENSG00000115808.7	STRN	0.65	0.22	3.15×10−3	0.045
17	cg13180678	ENSG00000214941.3	ZSWIM7	27.71	9.42	3.41×10−3	0.048

Results were obtained using linear regression, adjusting for age at death, sex, and education, and multiple testing were adjusted using false discovery rate (Q value< 0.05).

Beta is the estimated effect size.

CHR, chromosome; QTM: quantitative trait methylation; SE, standard error.