Table 3:

Associations between In Utero Exposures and Risk of High and Low AMH Compared to Normal AMH

Exposures	Low AMH <1.0ng/ml RR (95% CI)	Normal AMH 1.0 – 3.5ng/ml	High AMH >3.5 ng/ml RR (95% CI)
DES
Unadjusted	2.94 (0.89, 9.70)	Ref	1.44 (0.75, 2.75)
Adjusted	4.54 (0.61, 33.65)	Ref	0.98 (0.26, 3.73)
Vitamins
Unadjusted	0.53 (0.30, 0.93)	Ref	2.05 (1.36, 3.08)
Adjusted	0.67 (0.38, 1.19)	Ref	1.93 (1.24, 3.00)
Cigarettes
Unadjusted	1.46 (0.86, 2.47)	Ref	0.85 (0.65, 1.12)
Adjusted	1.14 (0.61, 2.11)	Ref	0.99 (0.72, 1.36)
Alcohol Use
Unadjusted	1.03 (0.44, 2.41)	Ref	0.99 (0.70, 1.4)
Adjusted	0.90 (0.29, 2.80)	Ref	1.06 (0.73, 1.56)
Caffeine Use
Unadjusted	1.80 (1.16, 2.80)	Ref	0.91 (0.78, 1.07)
Adjusted	1.90 (1.09, 3.30)	Ref	0.93 (0.77, 1.11)
Any work (full or part time)
Unadjusted	0.99 (0.68, 1.45)	Ref	0.83 (0.71, 0.99)
Adjusted	0.96 (0.59, 1.55)	Ref	0.86 (0.71, 1.05)
Working Part Time
Unadjusted	1.39 (0.83, 2.35)	Ref	0.79 (0.59, 1.06)
Adjusted	1.03 (0.55, 1.92)	Ref	0.93 (0.68, 1.28)
Working Full Time
Unadjusted	0.79 (0.50, 1.24)	Ref	0.91 (0.75, 1.09)
Adjusted	0.84 (0.47, 1.51)	Ref	0.88 (0.71, 1.09)

Bold indicates statistical significance at the α=0.05 level.

Adjusted models are adjusted for EAGeR participant age, mother’s age at birth of daughter, mother’s history of fertility treatment, and mother’s history of vitamin use (except where history of vitamin use was the main exposure of interest).

CI, confidence interval; RR, relative risk.