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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: BJOG. 2020 Sep 14;128(1):55–65. doi: 10.1111/1471-0528.16441

Table 2.

Disease categories and specific traits assessed using risk SNPs.

Disease category Trait
Cardiovascular Systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides, coronary artery disease (CAD), ischemic stroke
Inflammatory/ autoimmune C-reactive protein (CRP), systemic lupus erythematosus (SLE)
Insulin resistance Adiponectin, fasting blood glucose, type 2 diabetes mellitus (T2DM)
Liver Alkaline phosphatase (ALP), gamma-glutamyl transferase (GTT)
Obesity Body mass index (BMI), birthweight
Renal Estimated glomerular filtration rate from serum creatinine (eGFRCr), uric acid
Thrombophilia Fibrinogen, venous thromboembolism (VTE)