(a) Immunofluorescence image of SST-knockdown and control BON cells. Knockdown was accomplished by reverse-transfection with two siRNA against SST and a scrambled siRNA as a control. (b) Cell viability of SST-knockdown and control cells at day 3 and 6 post-transfection. Cell viability was determined using alamarBlue assay. (c) Immunofluorescence image of stable SST-knockdown and control cells. Knockdown was accomplished by infection with lentivirus encoding two shRNAs against SST and a scrambled shRNA as a control. (d) Cell count of stable SST-knockdown and control cells, determined by manual counting using a hemocytometer every two days. Data represent mean ± SEM from triplicates.
Abbreviations: short interfering RNA (siRNA), short hairpin RNA (shRNA), somatostatin (SST)