Table 3.
Cox proportional HRs associating baseline parameters with 3-year risk of death due to all causes.
| Univariate model | |||
|---|---|---|---|
| HR | 95%CI | p-value | |
| Male | 0.90 | 0.46–1.73 | 0.75 |
| Age (per years) | 1.05 | 1.01–1.08 | 0.01 |
| Smoking | |||
| Non-smoker | Ref | – | – |
| Past-smoker | 1.09 | 0.53–2.24 | 0.81 |
| Current-smoker | 1.68 | 0.70–4.00 | 0.24 |
| BMI (kg/m2) | |||
| < 18.5 | 2.21 | 1.12–4.36 | 0.02 |
| 18.5–24.9 | Ref | – | – |
| ≥ 25 | 0.36 | 0.09–1.55 | 0.17 |
| Hemodialysis vintage (per month) | 1.00 | 0.99–1.00 | 0.51 |
| Diabetes mellitus | 1.69 | 0.88–3.24 | 0.12 |
| Duration of DM (per year)a | 1.02 | 0.97–1.06 | 0.50 |
| Prior CVD event | 3.07 | 1.62–5.81 | 0.001 |
| White Blood Cell (per 103/μL) | 1.17 | 1.03–1.34 | 0.02 |
| Albumin (per g/dL) | 0.10 | 0.04–0.21 | < 0.001 |
| hsCRP (per mg/dL) | 1.94 | 1.61–2.35 | < 0.001 |
| Dental status | |||
| Number of teeth (per tooth) | 0.94 | 0.90–0.98 | 0.003 |
| Number of decayed teeth (per tooth) | 1.18 | 1.07–1.31 | 0.002 |
| Number of filled teeth (per tooth) | 0.90 | 0.84–0.97 | 0.004 |
| Oral hygiene status | |||
| DI-S (T3 versus T1-2) | 3.78 | 1.95–7.30 | < 0.001 |
| Frequency of tooth brushing (per time/day) | |||
| < 2 | Ref | – | – |
| ≥ 2 | 0.47 | 0.25–0.90 | 0.022 |
| Use of interdental cleaning tools | 0.46 | 0.18–1.17 | 0.10 |
| Periodontal parameters | |||
| Severity of periodontitis | |||
| Healthy | Ref | – | – |
| Mild | 2.64 | 0.33–19.42 | 0.33 |
| Moderate | 1.83 | 0.24–14.11 | 0.56 |
| Severe | 3.52 | 0.46–27.10 | 0.23 |
| PPD ≥ 4 mm (%) | |||
| < 10 | Ref | – | – |
| ≥ 10 | 1.86 | 0.95–3.64 | 0.07 |
| BOP (%) | |||
| < 10 | Ref | – | – |
| ≥ 10 | 1.48 | 0.78–2.80 | 0.23 |
| Number of P.gingivalis (per numbers/ml, log10) | 1.30 | 0.81–2.08 | 0.28 |
BMI, body mass index; BOP, bleeding on probing; BP, blood pressure; CVD, cardiovascular disease; DI-S, simplified debris index; hsCRP, high-sensitivity C-reactive protein; PPD, probing pocket depth; Ref, reference.
aRecords only for subjects with diabetes (n = 101).
bRecords only for subjects who P. gingivalis was detected (n = 115).