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. Author manuscript; available in PMC: 2022 Apr 15.
Published in final edited form as: Biol Psychiatry. 2020 Jun 15;89(8):795–806. doi: 10.1016/j.biopsych.2020.06.010

Table 2.

Associations between weighted connectome (edge and node) composites, total brain volume, and age-11 IQ.

Table 2a: Processing Speed
Composite Model Predictor 1 Predictor 2 β1 (p-value) β2 (p-value) R2 Multiple R
Age-based 1a - TBV - 0.165 (0.001) 0.027 0.165
1b Edges TBV −0.194 (< 0.0005) 0.165 (< 0.0005) 0.065 0.255
1c Nodes TBV −0.408 (< 0.0005) −0.188 (0.049) 0.069 0.263
2a Edges only - −0.193 (< 0.0005) - 0.037 0.193
2b - Nodes only - −0.245 (< 0.0005) 0.060 0.245
2c Edges Nodes −0.167 (< 0.0005) −0.226 (< 0.0005) 0.088 0.297
3a - Age 11 IQ - 0.511 (< 0.0005) 0.261 0.511
3b Edges Age 11 IQ −0.149 (0.001) 0.498 (< 0.0005) 0.282 0.531
3c Nodes Age 11 IQ −0.162 (< 0.0005) 0.484 (< 0.0005) 0.285 0.535
PC-based 4a - TBV - 0.165 (0.001) 0.027 0.165
4b Edges TBV 0.176 (< 0.0005) 0.163 (0.001) 0.058 0.241
4c Nodes TBV 0.382 (< 0.0005) −0.168 (0.089) 0.062 0.249
5a Edges only - 0.177 (< 0.0005) - 0.031 0.177
5b - Nodes only - 0.235 (< 0.0005) 0.055 0.235
5c Edges Nodes 0.154 (0.001) 0.219 (< 0.0005) 0.079 0.281
6a - Age 11 IQ - 0.511 (< 0.0005) 0.261 0.511
6b Edges Age 11 IQ 0.133 (0.002) 0.500 (< 0.0005) 0.277 0.526
6c Nodes Age 11 IQ 0.154 (< 0.0005) 0.486 (< 0.0005) 0.283 0.532
Table 2b: Visuospatial Ability
Composite Model Predictor 1 Predictor 2 β1 (p-value) β2 (p-value) R2 Multiple R
Age-based 1a - TBV - 0.333 (< 0.0005) 0.111 0.333
1b Edges TBV −0.087 (0.068) 0.331 (< 0.0005) 0.117 0.342
1c Nodes TBV −0.401 (< 0.0005) −0.017 (0.860) 0.149 0.386
2a Edges only - −0.089 (0.072) - 0.008 0.089
2b - Nodes only - −0.386 (< 0.0005) 0.149 0.386
2c Edges Nodes −0.043 (0.363) −0.380 (< 0.0005) 0.150 0.387
3a - Age 11 IQ - 0.553 (< 0.0005) 0.306 0.553
3b Edges Age 11 IQ −0.039 (0.387) 0.549 (< 0.0005) 0.307 0.554
3c Nodes Age 11 IQ −0.308 (< 0.0005) 0.504 (< 0.0005) 0.397 0.630
PC-based 4a - TBV - 0.333 (< 0.0005) 0.111 0.333
4b Edges TBV 0.058 (0.224) 0.331 (< 0.0005) 0.114 0.338
4c Nodes TBV 0.399 (< 0.0005) −0.019 (0.848) 0.147 0.383
5a Edges only - 0.064 (0.197) - 0.004 0.064
5b - Nodes only - 0.383 (< 0.0005) 0.147 0.383
5c Edges Nodes 0.023 (0.633) 0.380 (< 0.0005) 0.147 0.383
6a - Age 11 IQ - 0.553 (< 0.0005) 0.306 0.553
6b Edges Age 11 IQ 0.017 (0.702) 0.552 (< 0.0005) 0.306 0.553
6c Nodes Age 11 IQ 0.306 (< 0.0005) 0.505 (< 0.0005) 0.397 0.630
Table 2c: Memory
Composite Model Predictor 1 Predictor 2 β1 (p-value) β2 (p-value) R2 Multiple R
Age-based 1a - TBV - 0.012 (0.815) 0.0001 0.012
1b Edges TBV −0.082 (0.117) 0.009 (0.861) 0.007 0.084
1c Nodes TBV −0.446 (< 0.0005) −0.370 (< 0.0005) 0.049 0.221
2a Edges only - −0.083 (0.116) - 0.007 0.083
2b - Nodes only - −0.124 (0.014) 0.015 0.124
2c Edges Nodes −0.067 (0.204) −0.166 (0.023) 0.020 0.141
3a - Age 11 IQ - 0.613 (< 0.0005) 0.376 0.613
3b Edges Age 11 IQ −0.027 (0.557) 0.615 (< 0.0005) 0.381 0.617
3c Nodes Age 11 IQ −0.033 (0.468) 0.611 (< 0.0005) 0.381 0.617
PC-based 4a - TBV - 0.012 (0.815) 0.0001 0.012
4b Edges TBV 0.052 (0.329) 0.009 (0.863) 0.003 0.055
4c Nodes TBV 0.442 (< 0.0005) −0.369 (< 0.0005) 0.045 0.214
5a Edges only - 0.053 (0.324) - 0.003 0.053
5b - Nodes only - 0.118 (0.019) 0.014 0.118
5c Edges Nodes 0.037 (0.483) 0.114 (0.026) 0.015 0.122
6a - Age 11 IQ - 0.613 (< 0.0005) 0.376 0.613
6b Edges Age 11 IQ −0.003 (0.954) 0.616 (< 0.0005) 0.379 0.616
6c Nodes Age 11 IQ 0.029 (0.524) 0.612 (< 0.0005) 0.380 0.616

Note. TBV = Total brain volume.