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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Mol Cell Endocrinol. 2020 Oct 27;519:111063. doi: 10.1016/j.mce.2020.111063

Figure 4.

Figure 4.

Height of STAT5B deficient patients are comparable to GHR deficient patients. Height SDS values of GHI patients with GHR mutations (black) were compared with height SDS values of STAT5B mutation carriers (blue). Growth Hormone Receptor (GHR) Defects: AR, Autosomal Recessive GHR mutations (n=100); AR pseudoexon, GHR pseudoexon 6Ψ mutations (n=21); DN, Dominant Negative GHR mutations (n=16). STAT5B Defects: DN, Dominant Negative STAT5B mutations (n=11); AR, Autosomal Recessive STAT5B mutations (n=10); AR Carriers, STAT5B mutation carriers (n=14). Box (median, 25th and 75th percentiles) and whiskers (minimum and maximum values) plots; statistical analysis by Student’s t-test, * P<0.05; *** P<0.001; n.s., not significant. (Reproduced with permission from Klammt J, et al, Nat Commun 2018; 9:2105)