Table 1.
Differential expression of Human Hsp90 isoforms and cochaperones in the muscle and testis
| Cochaperone | Skeletal muscle Mean TPM | Testis Mean TPM | Function |
|---|---|---|---|
| FKBP51 | 176.7 | 28.8 | Promotes myogenesis |
| S100A1 | 21.7 | 2.8 | Localizes to Z-discs and sarcoplasmic reticulum |
| ITGB1BP2 | 7.7 | 2.4 | Integrin binding protein |
| UNC45B | 83.7 | 2.2 | Myosin chaperone |
| AARSD1 | 38.4 | 9.1 | Muscle wasting and GR activity |
| HARC | 40.5 | 18.0 | Mutations linked to heart failure |
| NASP | 15.4 | 106.4 | testis- and sperm-specific histone-binding protein |
| TOM34 | 12.6 | 293.0 | |
| PIH1D2 | 0.6 | 66.0 | Dynein assembly |
| FKBP36 | 0 | 76.7 | |
| HACD3 | 2.2 | 21.1 | |
| NUDCD1 | 3.7 | 18.2 | Dynein assembly |
| NCB5or | 2.7 | 12.9 | |
| LRRC6 | 0.1 | 32.1 | Dynein assembly |
| DYX1C1 | 0.2 | 11.0 | Dynein assembly |
| SPAG1 | 0.3 | 16.5 | Dynein assembly |
| PIH1D3 | 0 | 16.2 | Dynein assembly |
| HSP90AA1 | 239.4 | 902.0 | Hsp90 alpha |
| HSP90AB1 | 929.3 | 541.8 | Hsp90 beta |
TPM, transcripts per million (gtexportal.org)