Figure 7: LDH inhibition increases bone strength in mice.

Biomechanical properties of mice after treatment with OXA or PBS were assessed via femoral torsion testing. OXA-treated mice revealed (A) no change in torsional rigidity, but showed significant increases in (B) maximum torque, (C) maximal rotation, and (D) energy to yield. Data are presented as boxplots with actual data points, median, and range. P value was determined by unpaired t-test and shown in data sets with p < 0.05.