Figure 8. LDH inhibition improves trabecular and cortical bone in aged mice.
Effect of OXA on femur bone architecture was analyzed by micro-CT. OXA-treated mice showed increased (A) trabecular bone to total volume ratio and trabecular thickness and (B) cortical thickness, area, and bone mineral density (BMD). Data are presented as boxplots with actual data points, median, and range. P value was determined by unpaired t-test and shown in data sets with p < 0.05.