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. 2020 Dec 14;10:21881. doi: 10.1038/s41598-020-78930-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Principal component analysis of cerebral metabolomic changes 72 h after MCAO vs no surgery. CE-TOF MS data for 151 detected metabolites were subjected to principal component analysis after being split into four groups. (A) Score plot showing that the groups were well divided between the control (circle) and MCAO groups, excluding one outlier in the MCAO-CD34⁺ cell group (cross), according to the variation of principal component (PC) 1 (X-axis). (B) PC1 loading column plot of the top 20 metabolites. The listed metabolites strongly contributed to PC1, and vertical gray bars are distances in multivariate space between the average metabolite vectors for each group.