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. 2020 Dec 14;10:21881. doi: 10.1038/s41598-020-78930-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Multivariate analysis of cerebral metabolomic changes among the MCAO groups. Concentration data for 79 metabolites detected among the three MCAO groups were subjected to partial least-squares discriminant analysis (PLS-DA). The score plot illustrates the difference between the MCAO-vehicle group (triangle) and the MCAO-MSC group (diamond) (A). Variable importance in the projection (VIP) scores > 1 among the three MCAO groups were extracted and are shown in a score plot (B).