TABLE 2.

The k-fold cross-validation results of existed tools.

Tools*	Fold	Accuracy	Sensitivity	Specificity	AUC
MDD-SOH	5	0.68	0.7	0.7
SOHSite	5	0.71	0.72	0.72
SOHPRED	5		0.727 ± 0.005	0.742 ± 0.001	0.801 ± 0.001
iSulf-Cys	10	0.656 ± 0.007	0.673 ± 0.007	0.639 ± 0.001	0.716 ± 0.009
SulCysSite	10		0.745 ± 0.006	0.744 ± 0.002	0.806 ± 0.002
Sulf_FSVM	10	0.711 ± 0.002	0.733 ± 0.004	0.708 ± 0.002	0.788 ± 0.002
LSTMWE	10	0.739 ± 0.006	0.694 ± 0.042	0.744 ± 0.008	0.800 ± 0.011
RFEAAC	10	0.733 ± 0.006	0.607 ± 0.021	0.750 ± 0.007	0.753 ± 0.006
RFE+S+A	10	0.743 ± 0.009	0.728 ± 0.027	0.745 ± 0.009	0.807 ± 0.010

*The cross-validation dataset was derived from Yang’s publication (Yang et al., 2014).