Table 5.
The Common Genes Shared by TWAS and the Differently Expressed Genes Identified by mRNA Expression Profiles
| Ensemble ID | Gene Name | CHR | FC (OP/CTR) | Cell type |
|---|---|---|---|---|
| ENSG00000145332 | KLHL8 | 4 | 1.14 | Bone |
| ENSG00000152595 | MEPE | 4 | 0.6 | Bone |
| ENSG00000166949 | SMAD3 | 15 | 43.27 | MSC |
| ENSG00000029559 | IBSP | 4 | 9.41 | MSC |
| ENSG00000167941 | SOST | 17 | 4.6 | MSC |
| ENSG00000141349 | G6PC3 | 17 | 4.52 | MSC |
| ENSG00000127418 | FGFRL1 | 4 | 3.69 | MSC |
| ENSG00000127415 | IDUA | 4 | 2.84 | MSC |
| ENSG00000188554 | NBR1 | 17 | 2.77 | MSC |
| ENSG00000183023 | SLC8A1 | 2 | 2.59 | MSC |
| ENSG00000118785 | SPP1 | 4 | 2.53 | MSC |
| ENSG00000149091 | DGKZ | 11 | 2.47 | MSC |
| ENSG00000033050 | ABCF2 | 7 | 2.42 | MSC |
| ENSG00000108797 | CNTNAP1 | 17 | 2.13 | MSC |
| ENSG00000139055 | ERP27 | 12 | 2.12 | MSC |
| ENSG00000148943 | LIN7C | 11 | 2.04 | MSC |
| ENSG00000107164 | FUBP3 | 9 | 0.46 | MSC |
| ENSG00000090686 | USP48 | 1 | 0.45 | MSC |
| ENSG00000196937 | FAM3C | 7 | 0.44 | MSC |
| ENSG00000071243 | ING3 | 7 | 0.38 | MSC |
Abbreviations: CHR, chromosome; CTR, control; FC, fold change; MSC, mesenchymal stem cell; OP, osteoporosis; TWAS, transcriptome-wide association study.