TABLE 2.

Creatinine monitoring with tenofovir disoproxil fumarate pre-exposure prophylaxis.

Variable	At PrEP start	At PrEP follow-up
Well individual, ≤ 40 years	Recommended, not essential	Not required
> 40 years	Recommended	6 and 12 months
Pregnant	Recommended	6 and 12 months; not required after pregnancy if ≤ 40 years
Comorbidities	Recommended	6 and 12 months
Concomitant chronic medication	Recommended and essential or contra-indicated if nephrotoxic concomitant medication	6 and 12 months/contraindicated

PrEP, pre-exposure prophylaxis.