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. 2020 Dec 14;14(2):100991. doi: 10.1016/j.tranon.2020.100991

Table 5.

diagnostic performance of eight lung cancer-antigens in cohort 2.

Protein Description AUC (95% CI) Sensitivity (95% CI) Specificity (95% CI)
DDX6 0.8062 (0.7367 to 0.8905) 73.68% (62.32% to 83.13%) 75.44 (62.24% to 85.87%)
MCCC1 0.7762 (0.6912 to 0.8593) 70.00% (56.79% to 81.15%) 71.67% (58.56% to 82.55%)
ENO1 0.7747 (0.6883 to 0.8611) 75.00% (62.14% to 85.28%) 70.00% (56.79% to 81.15%)
FBXO38 0.7686 (0.6864 to 0.8508) 61.67% (48.21% to 73.93%) 70.00% (56.79% to 81.15%)
14–3–3ζ 0.7656 (0.6789 to 0.8522) 58.33% (44.88% to 70.93%) 78.62% (67.67% to 89.22%)
CSNK1D 0.7615 (0.6744 to 0.8473) 71.67% (58.56% to 82.55%) 73.33% (60.34% to 83.93%)
ESO-1 0.7358 (0.6457 to 0.8259) 70.00% (56.79% to 81.15%) 65.00% (51.60% to 76.87%)
MUC1 0.6636 (0.5634 to 0.7639) 60.34% (46.64% to 72.95%) 60.34% (46.64% to 72.95%)
Combined use of three TAAbs 0.8667 (0.7935 to 0.9499) 81.36% (69.09% to 90.31)% 83.33% (71.48% to 91.71%)

Abbreviations: AUC, the area under receiver operating characteristic curve; CI, confidence interval.