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. 2020 Nov 10;48(22):12436–12452. doi: 10.1093/nar/gkaa1053

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Comparison between in vitro and in vivo structure of the SARS-CoV-2 genome. (A) Heat scatter plot of normalized SHAPE reactivities for the in vitro refolded SARS-CoV-2 genome versus the in vivo-probed one. (B) Distribution of SHAPE reactivities for the in vitro refolded SARS-CoV-2 genome, versus the in vivo-probed one. (C) Violin plot depicting the distribution of Gini indexes calculated in 50 nt windows slid along the SARS-CoV-2 genome for the in vitro refolded sample versus the in vivo-probed one (sliding offset: 25 nt).