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. 2020 Nov 27;48(22):12917–12928. doi: 10.1093/nar/gkaa1128

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — AFM images of control and AU-tract dsRNA sequences. (A) Representative AFM image of control molecules with a zoom-in image of the marked region showing an example of a typical trace. Additional AFM images are shown in Supplementary Figure S7. Inset, cartoon depicting a segment of a trace. In black, we represented the end-to-end distance, , between two points separated by a contour distance 15 nm and the angle defined by the tangents at those points,. Those same points are considered together with a third, middle point located at 7.5 nm from each of them (purple points) to fit a circle of radius (in green). The distance between two adjacent points of the trace is 2.5 nm. (B) Representative AFM images of ExpAU-4 and (C), ExpAU-5 molecules. Z-scale is the same as in A.

Inline graphic — AFM images of control and AU-tract dsRNA sequences. (A) Representative AFM image of control molecules with a zoom-in image of the marked region showing an example of a typical trace. Additional AFM images are shown in Supplementary Figure S7. Inset, cartoon depicting a segment of a trace. In black, we represented the end-to-end distance, , between two points separated by a contour distance 15 nm and the angle defined by the tangents at those points,. Those same points are considered together with a third, middle point located at 7.5 nm from each of them (purple points) to fit a circle of radius (in green). The distance between two adjacent points of the trace is 2.5 nm. (B) Representative AFM images of ExpAU-4 and (C), ExpAU-5 molecules. Z-scale is the same as in A.