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. 2020 Dec 4;48(22):12632–12647. doi: 10.1093/nar/gkaa1149

Figure 2.

Figure 2.

Phylogeny of retron/retron-like RTs and associated ncRNA structures. (A) Phylogenetic reconstruction of retron/retron-like RTs. The tree is provided as a newick file in Supplementary File S1. The different colors represent the different types/variants identified as clustering in different phylogenetic groups. The outer lines indicate the phylogenetic clades. RTs belonging to experimentally validated retrons are indicated, and their nomenclature is included. Note that Vc137 correspond in Supplementary Table S1 to entry 1575 (fig|1343738.3.peg.2232) present in the data set of 1,912 retron/retron-like RT sequences. (B) Consensus IA/IIA1 msr/msd transcript structure. The different regions of the msr/msd transcript are highlighted in color: msr (blue), msd (orange), a1/a2 (yellow). The two opposing G residues are highlighted in magenta. An alignment of the msr/msd transcript with 10 representative sequences is shown below, in which positions with >90% gaps were removed. Other consensus ncRNA structures identified are shown in Supplementary Figure S1.