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. 2020 Dec 7;13:4809–4822. doi: 10.2147/DMSO.S281527

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© 2020 Shaher et al.

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Effect of Ganoderma lucidum spores (GLS) on the protein expression of p-PI3K, p-Akt, and p-mTOR according to immunohistochemical results (A, C and E) and their statistical analysis (B, D and F) in cardiac tissues in different groups. (Micrographs, magnification 400×. Arrows indicate the changed areas. Values represent the mean ± SE; n = 3 in each group. **, p < 0.01 versus the control group and ^##, p < 0.01 versus STZ group using Tukey’s test. Control: 5 mL/kg saline (p.o.); Diabetic: 50 mg/kg streptozotocin (i.p.) and 5 mL/kg saline (p.o.); STZ+GLS: 50 mg/kg streptozotocin (i.p.) and 300 mg/kg GLS (p.o.).